Website under development. Last compiled on 2026-09-30 at 11:36 PM PDT.

Welcome

Welcome to the Metapopulation Outbreak Simulation with Agent-based Implementation for Cholera (MOSAIC). The MOSAIC framework simulates the transmission dynamics of cholera in Sub-Saharan Africa (SSA) and provides tools to understand the impact of interventions, such as vaccination, as well as large-scale drivers like climate change. MOSAIC’s transmission engine was first built on the Light-agent Spatial Model for ERadication (LASER) platform, in the laser-cholera package, and now runs as a pure-R port of that engine inside the MOSAIC R package; this site serves as documentation for the model’s methods and associated analyses. Please note that MOSAIC is currently under development, so content may change regularly. We are sharing it here to increase visibility and welcome feedback on any aspect of the model.

Contact

MOSAIC is developed by a team of researchers at the Institute for Disease Modeling (IDM) dedicated to developing modeling methods and software tools that help decision-makers understand and respond to infectious disease outbreaks. This website is currently maintained by John Giles (@gilesjohnr). For general questions, contact John Giles (), Jillian Gauld (), and/or Rajiv Sodhi (). The MOSAIC R package also benefits from contributions by Christopher Lorton, Tony Ting, Dejan Lukacevic, and Meikang Wu.

Funding

This work was developed at the Institute for Disease Modeling in support of funded research grants made by the Bill & Melinda Gates Foundation.

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