Vector control

The following parameters determine the characteristics of campaign interventions aimed at vector control, such as the homing endonuclease gene (HEG), sugar feeding, and Wolbachia infection. When, to whom, and how those interventions are distributed is determined by the campaign file.

Note

Parameters are case-sensitive. For Boolean parameters, set to 1 for true or 0 for false. Minimum, maximum, or default values of “NA” indicate that those values are not applicable for that parameter.

EMOD does not use true defaults; that is, if the dependency relationships indicate that a parameter is required, you must supply a value for it. However, many of the tools used to work with EMOD will use the default values provided below.

JSON format does not permit comments, but you can add “dummy” parameters to add contextual information to your files. Any keys that are not EMOD parameter names will be ignored by the model.

Parameter

Data type

Minimum

Maximum

Default

Description

Example

HEG_Fecundity_Limiting

float

0

1

0

The fractional reduction in the number of eggs laid by a female mosquito who is homozygous in the homing endonuclease gene (HEG). HEG_Model must be set to GERMLINE_HOMING, EGG_HOMING, DUAL_GERMLINE_HOMING, or DRIVING_Y.

{
    "HEG_Model": "EGG_HOMING",
    "HEG_Fecundity_Limiting": 0.7
}

HEG_Homing_Rate

float

0

1

0

The fractional redistribution from heterozygous offspring to the homozygous homing endonuclease gene (HEG) behavior. HEG_Model” must be set to GERMLINE_HOMING, EGG_HOMING, DUAL_GERMLINE_HOMING, or DRIVING_Y.

{
    "HEG_Model": "EGG_HOMING",
    "HEG_Homing_Rate": 0.4
}

HEG_Model

enum

NA

NA

OFF

This parameter determines the structure of homing endonuclease gene (HEG) dynamics. Possible values are:

OFF

No HEG dynamics occur.

GERMLINE_HOMING

Female mosquito allele applies homing and then the fraction of wild/half/full HEG progeny are generated from combining with the male allele.

EGG_HOMING

The fraction of wild/half/full HEG progeny are calculated and then homing is applied to bias half towards full.

DUAL_GERMLINE_HOMING

Both male and female alleles apply germline bias before calculating progeny.

DRIVING_Y

Homing is applied as a bias of otherwise heterozygous progeny to be Y-drive male eggs.

{
    "HEG_Model": "EGG_HOMING",
    "HEG_Homing_Rate": 0.4,
    "HEG_Fecundity_Limiting": 0.9
}

Vector_Sugar_Feeding_Frequency

enum

NA

NA

VECTOR_SUGAR_FEEDING_NONE

The frequency of sugar feeding by a female mosquito. Used is used in conjunction with the SugarTrap and OvipositionTrap interventions. Vector_Sampling_Type must be set to TRACK_ALL_VECTORS or SAMPLE_IND_VECTORS. Possible values are:

VECTOR_SUGAR_FEEDING_NONE

No sugar feeding.

VECTOR_SUGAR_FEEDING_ON_EMERGENCE_ONLY

Sugar feeding once at emergence.

VECTOR_SUGAR_FEEDING_EVERY_FEED

Sugar feeding occurs once per blood meal.

VECTOR_SUGAR_FEEDING_EVERY_DAY

Sugar feeding occurs every day.

{
    "Vector_Sugar_Feeding_Frequency": "VECTOR_SUGAR_FEEDING_NONE"
}

Wolbachia_Infection_Modification

float

0

100

1

The change in vector susceptibility to infection due to a Wolbachia infection.

{
    "Wolbachia_Infection_Modification": 1.0
}

Wolbachia_Mortality_Modification

float

0

100

1

The change in vector mortality due to a Wolbachia infection.

{
    "Wolbachia_Infection_Modification": 0.0
}