SimpleVaccine

The SimpleVaccine intervention class implements vaccine campaigns in the simulation. Vaccines can have an effect on one of the following:

  • Reduce the likelihood of acquiring an infection

  • Reduce the likelihood of transmitting an infection

  • Reduce the likelihood of death

To configure vaccines that have an effect on more than one of these, use MultiEffectVaccine instead.

Note

Parameters are case-sensitive. For Boolean parameters, set to 1 for true or 0 for false. JSON does not permit comments, but you can add “dummy” parameters to add contextual information to your files.

The table below describes all possible parameters with which this class can be configured. The JSON example that follows shows one potential configuration.

Parameter

Data type

Minimum

Maximum

Default

Description

Example

Vaccine_Take

float

0

1

1

The rate at which delivered vaccines will successfully stimulate an immune response and achieve the desired efficacy. For example, if it is set to 0.9, there will be a 90 percent chance that the vaccine will start with the specified efficacy, and a 10 percent chance that it will have no efficacy at all.

{
    "Intervention_Config": {
        "class": "SimpleVaccine",
        "Cost_To_Consumer": 10,
        "Vaccine_Type": "AcquisitionBlocking",
        "Vaccine_Take": 1,
        "Efficacy_Is_Multiplicative": 0,
        "Waning_Config": {
            "class": "WaningEffectConstant",
            "Initial_Effect": 0.3
        }
    }
}

Vaccine_Type

enum

NA

NA

Generic

The type of vaccine to distribute in a vaccine intervention. Possible values are:

Generic

The vaccine can reduce transmission, acquisition, and mortality.

TransmissionBlocking

The vaccine will reduce pathogen transmission.

AcquisitionBlocking

The vaccine will reduce the acquisition of the pathogen by reducing the force of infection experienced by the vaccinated individual.

MortalityBlocking

The vaccine reduces the disease-mortality rate of a vaccinated individual.

{
    "Intervention_Config": {
        "class": "SimpleVaccine",
        "Cost_To_Consumer": 10,
        "Vaccine_Type": "AcquisitionBlocking",
        "Vaccine_Take": 1,
        "Efficacy_Is_Multiplicative": 0,
        "Waning_Config": {
            "class": "WaningEffectConstant",
            "Initial_Effect": 0.3
        }
    }
}

Efficacy_Is_Multiplicative

boolean

NA

NA

1

The overall vaccine efficacy when individuals receive more than one vaccine. When set to true (1), the vaccine efficacies are multiplied together; when set to false (0), the efficacies are additive.

{
    "Intervention_Config": {
        "class": "SimpleVaccine",
        "Cost_To_Consumer": 10,
        "Vaccine_Type": "AcquisitionBlocking",
        "Vaccine_Take": 1,
        "Efficacy_Is_Multiplicative": 0,
        "Waning_Config": {
            "class": "WaningEffectConstant",
            "Initial_Effect": 0.3
        }
    }
}

Dont_Allow_Duplicates

boolean

NA

NA

0

If an individual’s container has an intervention, set to true (1) to prevent them from receiving another copy of the intervention. Supported by all intervention classes.

{
    "Dont_Allow_Duplicates": 0
}

Waning_Config

JSON object

NA

NA

NA

The configuration of how the intervention efficacy wanes over time. Specify how this effect decays over time using one of the Waning effect classes.

{
    "Waning_Config": {
        "Box_Duration": 3650,
        "Initial_Effect": 1,
        "class": "WaningEffectBox"
    }
}

Cost_To_Consumer

float

0

999999

10

The unit cost per vaccine (unamortized).

{
    "Cost_To_Consumer": 10.0
}

Event_Or_Config

enum

NA

NA

Config

Specifies whether the current intervention (or a positive diagnosis, depending on the intervention class) distributes a nested intervention (the Config option) or an event will be broadcast which may trigger other interventions in the campaign file (the Event option). Possible values are:

  • Event

  • Config

{
    "Event_Or_Config": "Config"
}

Base_Sensitivity

float

0

1

1

The sensitivity of the diagnostic. This sets the proportion of the time that individuals with the condition being tested receive a positive diagnostic test. When set to 1, the diagnostic always accurately reflects the condition. When set to zero, then individuals who have the condition always receive a false-negative diagnostic test.

{
    "Base_Sensitivity": 0.8
}

Base_Specificity

float

0

1

1

The specificity of the diagnostic. This sets the proportion of the time that individuals without the condition being tested receive a negative diagnostic test. When set to 1, the diagnostic always accurately reflects the lack of having the condition. When set to zero, then individuals who do not have the condition always receive a false-positive diagnostic test.

{
    "Base_Specificity": 0.9
}

New_Property_Value

string

NA

NA

NA

An optional IndividualProperty key:value pair that will be assigned when the intervention is distributed. See NodeProperties and IndividualProperties parameters for more information. Generally used to indicate the broad category of health care cascade to which an intervention belongs to prevent individuals from accessing care through multiple pathways. For example, if an individual must already be taking a particular medication to be prescribed a new one.

{
    "New_Property_Value": "InterventionStatus:None"
}

Disqualifying_Properties

string

NA

NA

NA

A list of IndividualProperty key:value pairs that cause an intervention to be aborted (persistent interventions will stop being distributed to individuals with these values). See NodeProperties and IndividualProperties parameters for more information. Generally used to control the flow of health care access. For example, to prevent the same individual from accessing health care via two different routes at the same time.

{
    "Disqualifying_Properties": [
        "InterventionStatus:LostForever"
    ]
}

Intervention_Name

string

NA

NA

NA

The optional name used to refer to this intervention as a means to differentiate it from others that use the same class.

{
    "Intervention_Name":"Diagnostic_Sample"
}
{
    "Events": [{
        "class": "CampaignEvent",
        "Nodeset_Config": {
            "class": "NodeSetAll"
        },
        "Start_Day": 60,
        "Event_Coordinator_Config": {
            "class": "StandardInterventionDistributionEventCoordinator",
            "Target_Demographic": "Everyone",
            "Demographic_Coverage": 0.5,
            "Intervention_Config": {
                "class": "SimpleVaccine",
                "Cost_To_Consumer": 10.0,
                "Reduced_Transmit": 0,
                "Vaccine_Take": 1,
                "Vaccine_Type": "AcquisitionBlocking",
                "Waning_Config": {
                    "Box_Duration": 3650,
                    "Initial_Effect": 1,
                    "class": "WaningEffectBox"
                }
            }
        }
    }],
    "Use_Defaults": 1
}