Symptoms and diagnosis¶
The following parameters determine the characteristics of tuberculosis diagnosis and symptoms.
Note
Parameters are case-sensitive. For Boolean parameters, set to 1 for true or 0 for false. Minimum, maximum, or default values of “NA” indicate that those values are not applicable for that parameter.
EMOD does not use true defaults; that is, if the dependency relationships indicate that a parameter is required, you must supply a value for it. However, many of the tools used to work with EMOD will use the default values provided below.
JSON format does not permit comments, but you can add “dummy” parameters to add contextual information to your files. Any keys that are not EMOD parameter names will be ignored by the model.
Parameter |
Data type |
Minimum |
Maximum |
Default |
Description |
Example |
|---|---|---|---|---|---|---|
Days_Between_Symptomatic_And_Death_Weibull_Heterogeneity |
float |
0.1 |
10 |
1 |
The time between the onset of AIDS symptoms and death is sampled from a Weibull distribution; this parameter governs the heterogeneity (inverse shape) of the Weibull. |
{
"Days_Between_Symptomatic_And_Death_Weibull_Heterogeneity": 0.5
}
|
Days_Between_Symptomatic_And_Death_Weibull_Scale |
float |
1 |
3650 |
183 |
The time between the onset of AIDS symptoms and death is sampled from a Weibull distribution; this parameter governs the scale of the Weibull. |
{
"Days_Between_Symptomatic_And_Death_Weibull_Scale": 618.3
}
|
TB_Extrapulmonary_Fraction_Adult |
float |
0 |
1 |
0 |
The fraction of active cases in adults (age 15 or over) that are extrapulmonary. The sum of this and TB_Smear_Positive_Fraction_Adult must be less than or equal to 1. Extrapulmonary individuals are considered non-infectious. |
{
"TB_Extrapulmonary_Fraction_Adult": 0.33
}
|
TB_Extrapulmonary_Fraction_Child |
float |
0 |
1 |
0 |
The fraction of active cases in children (under age 15) that are extrapulmonary. The sum of this and TB_Smear_Positive_Fraction_Child must be less than or equal to 1. Extrapulmonary individuals are considered non-infectious. |
{
"TB_Extrapulmonary_Fraction_Child": 0.33
}
|
TB_Smear_Negative_Infectivity_Multiplier |
float |
0 |
1 |
0.25 |
The scale factor for Base_Infectivity to give the infectiousness of active smear-negative individuals. |
{
"TB_Smear_Negative_Infectivity_Multiplier": 1
}
|
TB_Smear_Negative_Mortality_Multiplier |
float |
0 |
1 |
0.4 |
The scale factor to increase the mortality rate set by TB_Active_Mortality_Rate for individuals with smear-negative TB. In the absence of treatment, the product is added to TB_Active_Cure_Rate and TB_Inactivation_Rate to determine the total rate of the active smear-negative state, then the ratio of the aforementioned product to total rate determines the probability that an active smear-negative individual will die from TB disease after mean duration of 1 / total rate. |
{
"TB_Smear_Negative_Mortality_Multiplier": 1
}
|
TB_Smear_Positive_Fraction_Adult |
float |
0 |
1 |
1 |
The fraction of active cases in adults (age 15 and over) that are smear-positive. The sum of TB_Smear_Positive_Fraction_Adult and TB_Extrapulmonary_Fraction_Adult must be less than or equal to 1. This sum plus the fraction of smear-negative adults is equal to 1. |
{
"TB_Smear_Positive_Fraction_Adult": 1
}
|
TB_Smear_Positive_Fraction_Child |
float |
0 |
1 |
1 |
The fraction of active cases in children (under age 15) that are smear-positive. The sum of TB_Smear_Positive_Fraction_Child and TB_Extrapulmonary_Fraction_Child must be less than or equal to 1. This sum plus the fraction of smear-negative children is equal to 1. |
{
"TB_Smear_Positive_Fraction_Child": 1
}
|