Symptoms and diagnosis#

The following parameters determine the characteristics of HIV diagnosis and HIV/AIDS symptoms, such as CD4 counts at various times in the progression of the disease.

Note

Parameters are case-sensitive. For Boolean parameters, set to 1 for true or 0 for false. Minimum, maximum, or default values of “NA” indicate that those values are not applicable for that parameter.

EMOD does not use true defaults; that is, if the dependency relationships indicate that a parameter is required, you must supply a value for it. However, many of the tools used to work with EMOD will use the default values provided below.

JSON format does not permit comments, but you can add “dummy” parameters to add contextual information to your files. Any keys that are not EMOD parameter names will be ignored by the model.

Parameter

Data type

Minimum

Maximum

Default

Description

Example

CD4_At_Death_LogLogistic_Scale

float

1

1000

31.63

The scale parameter of a Weibull distribution that represents the at-death CD4 cell count.

 
{
    "CD4_At_Death_LogLogistic_Scale": 2.96
}

CD4_Post_Infection_Weibull_Heterogeneity

float

0

100

0.275642

The inverse shape parameter of a Weibull distribution that represents the post-acute-infection CD4 cell count.

 
{
    "CD4_Post_Infection_Weibull_Heterogeneity": 0
}

CD4_Post_Infection_Weibull_Scale

float

1

1000

560.432

The scale parameter of a Weibull distribution that represents the post-acute-infection CD4 cell count.

 
{
    "CD4_Post_Infection_Weibull_Scale": 550
}

Days_Between_Symptomatic_And_Death_Weibull_Heterogeneity

float

0.1

10

1

The time between the onset of AIDS symptoms and death is sampled from a Weibull distribution; this parameter governs the heterogeneity (inverse shape) of the Weibull.

 
{
    "Days_Between_Symptomatic_And_Death_Weibull_Heterogeneity": 0.5
}

Days_Between_Symptomatic_And_Death_Weibull_Scale

float

1

3650

183

The time between the onset of AIDS symptoms and death is sampled from a Weibull distribution; this parameter governs the scale of the Weibull.

 
{
    "Days_Between_Symptomatic_And_Death_Weibull_Scale": 618.3
}