ControlledVaccine

The ControlledVaccine intervention class is a subclass of SimpleVaccine so it contains all functionality of SimpleVaccine, but provides more control over additional events and event triggers. This intervention can be configured so that specific events are broadcast when individuals receive an intervention or when the intervention expires. Further, individuals can be re-vaccinated, using a configurable wait time between vaccinations.

Note that one of the controls of this intervention is to not allow a person to receive an additional dose if they received a dose within a certain amount of time. This applies only to ControlledVaccine interventions with the same Intervention_Name, so people can be given multiple vaccines as long as each vaccine has a different value for Intervention_Name.

Note

Parameters are case-sensitive. For Boolean parameters, set to 1 for true or 0 for false. Minimum, maximum, or default values of “NA” indicate that those values are not applicable for that parameter.

EMOD does not use true defaults; that is, if the dependency relationships indicate that a parameter is required, you must supply a value for it. However, many of the tools used to work with EMOD will use the default values provided below.

JSON format does not permit comments, but you can add “dummy” parameters to add contextual information to your files. Any keys that are not EMOD parameter names will be ignored by the model.

The table below describes all possible parameters with which this class can be configured. The JSON example that follows shows one potential configuration.

Parameter

Data type

Minimum

Maximum

Default

Description

Example

Cost_To_Consumer

float

0

999999

10

The unit cost per vaccine (unamortized).

{
  "Cost_To_Consumer": 10.0
}

Disqualifying_Properties

array of strings

NA

NA

[]

A list of IndividualProperty key:value pairs that cause an intervention to be aborted (persistent interventions will stop being distributed to individuals with these values). See NodeProperties and IndividualProperties parameters for more information. Generally used to control the flow of health care access. For example, to prevent the same individual from accessing health care via two different routes at the same time.

{
  "Disqualifying_Properties": [
    "InterventionStatus:LostForever"
  ]
}

Distributed_Event_Trigger

enum

NA

NA

NA

The name of the event to be broadcast when the intervention is distributed to an individual. See Event list for possible values. Custom events can be distributed if they are defined in the config parameter Custom_Individual_Events.

{
  "Distributed_Event_Trigger": "Vaccinated"
}

Dont_Allow_Duplicates

boolean

0

1

0

If an individual’s container has an intervention, set to true (1) to prevent them from receiving another copy of the intervention. Supported by all intervention classes.

{
  "Dont_Allow_Duplicates": 0
}

Duration_To_Wait_Before_Revaccination

float

0

3.40E+38

3.40E+38

The length of time, in days, to wait before revaccinating an individual. After this time has passed, the individual can be revaccinated. If the first vaccine has not expired, the individual can receive the effect from both doses of the vaccine.

{
  "Duration_To_Wait_Before_Revaccination": 240
}

Efficacy_Is_Multiplicative

boolean

0

1

1

The overall vaccine efficacy when individuals receive more than one vaccine. When set to true (1), the vaccine efficacies are multiplied together; when set to false (0), the efficacies are additive.

{
  "Intervention_Config": {
    "Cost_To_Consumer": 10,
    "Efficacy_Is_Multiplicative": 0,
    "Vaccine_Take": 1,
    "Vaccine_Type": "AcquisitionBlocking",
    "Waning_Config": {
      "Initial_Effect": 0.3,
      "class": "WaningEffectConstant"
    },
    "class": "ControlledVaccine"
  }
}

Expired_Event_Trigger

enum

NA

NA

“”

The name of the event to be broadcast when the intervention is distributed to an individual. See Event list for possible values. Custom events can be distributed if they are defined in the config parameter Custom_Individual_Events.

{
  "Expired_Event_Trigger": "VaccineExpired"
}

Intervention_Name

string

NA

NA

ControlledVaccine

The optional name used to refer to this intervention as a means to differentiate it from others that use the same class.

{
  "Intervention_Config": {
    "class": "ControlledVaccine",
    "Intervention_Name": "Round of three measles vaccinations"
  }
}

New_Property_Value

string

NA

NA

“”

An optional IndividualProperty key:value pair that will be assigned when the intervention is applied. See NodeProperties and IndividualProperties parameters for more information. Generally used to indicate the broad category of health care cascade to which an intervention belongs to prevent individuals from accessing care through multiple pathways. For example, if an individual must already be taking a particular medication to be prescribed a new one.

{
  "New_Property_Value": "InterventionStatus:None"
}

Vaccine_Take

float

0

1

1

The rate at which delivered vaccines will successfully stimulate an immune response and achieve the desired efficacy. For example, if it is set to 0.9, there will be a 90 percent chance that the vaccine will start with the specified efficacy, and a 10 percent chance that it will have no efficacy at all.

{
  "Intervention_Config": {
    "Cost_To_Consumer": 10,
    "Efficacy_Is_Multiplicative": 0,
    "Vaccine_Take": 1,
    "Vaccine_Type": "AcquisitionBlocking",
    "Waning_Config": {
      "Initial_Effect": 0.3,
      "class": "WaningEffectConstant"
    },
    "class": "ControlledVaccine"
  }
}

Vaccine_Type

enum

NA

NA

Generic

The type of vaccine to distribute in a vaccine intervention. Possible values are:

Generic

The vaccine can reduce transmission, acquisition, and mortality.

TransmissionBlocking

The vaccine will reduce pathogen transmission.

AcquisitionBlocking

The vaccine will reduce the acquisition of the pathogen by reducing the force of infection experienced by the vaccinated individual.

MortalityBlocking

The vaccine reduces the disease-mortality rate of a vaccinated individual.

{
  "Intervention_Config": {
    "Cost_To_Consumer": 10,
    "Efficacy_Is_Multiplicative": 0,
    "Vaccine_Take": 1,
    "Vaccine_Type": "AcquisitionBlocking",
    "Waning_Config": {
      "Initial_Effect": 0.3,
      "class": "WaningEffectConstant"
    },
    "class": "ControlledVaccine"
  }
}

Waning_Config

json object

NA

NA

NA

The configuration of how the intervention efficacy wanes over time. Specify how this effect decays over time using one of the Waning effect classes.

{
  "Waning_Config": {
    "Box_Duration": 3650,
    "Initial_Effect": 1,
    "class": "WaningEffectBox"
  }
}
{
    "Use_Defaults": 1,
    "Events": [{
            "COMMENT": "Vaccinate Everyone with VaccineA",
            "class": "CampaignEvent",
            "Start_Day": 1,
            "Nodeset_Config": {
                "class": "NodeSetAll"
            },
            "Event_Coordinator_Config": {
                "class": "StandardInterventionDistributionEventCoordinator",
                "Target_Demographic": "Everyone",
                "Demographic_Coverage": 1.0,
                "Intervention_Config": {
                    "class": "ControlledVaccine",
                    "Intervention_Name": "VaccineA",
                    "Cost_To_Consumer": 1,
                    "Vaccine_Type": "AcquisitionBlocking",
                    "Vaccine_Take": 1.0,
                    "Waning_Config": {
                        "class": "WaningEffectMapLinear",
                        "Initial_Effect": 1.0,
                        "Expire_At_Durability_Map_End": 1,
                        "Durability_Map": {
                            "Times": [0, 25, 50],
                            "Values": [1.0, 1.0, 0.0]
                        }
                    },
                    "Distributed_Event_Trigger": "VaccinatedA",
                    "Expired_Event_Trigger": "VaccineExpiredA",
                    "Duration_To_Wait_Before_Revaccination": 40
                }
            }
        },
        {
            "COMMENT": "After the first round expires, distribute a different vaccine, VaccineB",
            "class": "CampaignEvent",
            "Start_Day": 60,
            "Nodeset_Config": {
                "class": "NodeSetAll"
            },
            "Event_Coordinator_Config": {
                "class": "StandardInterventionDistributionEventCoordinator",
                "Target_Demographic": "Everyone",
                "Demographic_Coverage": 1.0,
                "Intervention_Config": {
                    "class": "ControlledVaccine",
                    "Intervention_Name": "VaccineB",
                    "Cost_To_Consumer": 1,
                    "Vaccine_Type": "AcquisitionBlocking",
                    "Vaccine_Take": 1.0,
                    "Waning_Config": {
                        "class": "WaningEffectMapLinear",
                        "Initial_Effect": 1.0,
                        "Expire_At_Durability_Map_End": 1,
                        "Durability_Map": {
                            "Times": [0, 25, 50],
                            "Values": [1.0, 1.0, 0.0]
                        }
                    },
                    "Distributed_Event_Trigger": "VaccinatedB",
                    "Expired_Event_Trigger": "VaccineExpiredB",
                    "Duration_To_Wait_Before_Revaccination": 40
                }
            }
        }
    ]
}