IndividualImmunityChanger#
The IndividualImmunityChanger intervention class acts essentially as a MultiEffectVaccine, with the exception of how the behavior is implemented. Rather than attaching a persistent vaccine intervention object to an individual’s intervention list (as a campaign-individual-multieffectboostervaccine does), the IndividualImmunityChanger directly alters the immune modifiers of the individual’s susceptibility object and is then immediately disposed of. Any immune waning is not governed by Waning effect classes, as MultiEffectVaccine is, but rather by the immunity waning parameters in the configuration file.
Note
Parameters are case-sensitive. For Boolean parameters, set to 1 for true or 0 for false. Minimum, maximum, or default values of “NA” indicate that those values are not applicable for that parameter.
EMOD does not use true defaults; that is, if the dependency relationships indicate that a parameter is required, you must supply a value for it. However, many of the tools used to work with EMOD will use the default values provided below.
JSON format does not permit comments, but you can add “dummy” parameters to add contextual information to your files. Any keys that are not EMOD parameter names will be ignored by the model.
The table below describes all possible parameters with which this class can be configured. The JSON example that follows shows one potential configuration.
Parameter |
Data type |
Minimum |
Maximum |
Default |
Description |
Example |
---|---|---|---|---|---|---|
Boost_Acquire |
float |
0 |
1 |
0 |
Specifies the boosting effect on acquisition immunity for naive individuals (without natural or vaccine-derived immunity) for a multi-effect booster vaccine. This does not replace current immunity, it builds multiplicatively on top of it. |
{
"Boost_Acquire": 0.7
}
|
Boost_Mortality |
float |
0 |
1 |
0 |
Specifies the boosting effect on mortality immunity for naive individuals (without natural or vaccine-derived immunity) for a multi-effect booster vaccine. This does not replace current immunity, it builds multiplicatively on top of it. |
{
"Boost_Mortality": 1.0
}
|
Boost_Threshold_Acquire |
float |
0 |
1 |
0 |
Specifies how much acquisition immunity is required before the vaccine changes from a prime to a boost. |
{
"Boost_Threshold_Acquire": 0.0
}
|
Boost_Threshold_Mortality |
float |
0 |
1 |
0 |
Specifies how much mortality immunity is required before the vaccine changes from a prime to a boost. |
{
"Boost_Threshold_Mortality": 0.0
}
|
Boost_Threshold_Transmit |
float |
0 |
1 |
0 |
Specifies how much transmission immunity is required before the vaccine changes from a prime to a boost. |
{
"Boost_Threshold_Transmit": 0.0
}
|
Boost_Transmit |
float |
0 |
1 |
0 |
Specifies the boosting effect on transmission immunity for naive individuals (without natural or vaccine-derived immunity) for a multi-effect booster vaccine. This does not replace current immunity, it builds multiplicatively on top of it. |
{
"Boost_Transmit": 0.5
}
|
Cost_To_Consumer |
float |
0 |
999999 |
1 |
The unit cost per vaccine (unamortized). |
{
"Cost_To_Consumer": 10.0
}
|
Prime_Acquire |
float |
0 |
1 |
0 |
Specifies the priming effect on acquisition immunity for naive individuals (without natural or vaccine-derived immunity) for a multi-effect booster vaccine. |
{
"Prime_Acquire": 0.1
}
|
Prime_Mortality |
float |
0 |
1 |
0 |
Specifies the priming effect on mortality immunity for naive individuals (without natural or vaccine-derived immunity) for a multi-effect booster vaccine. |
{
"Prime_Mortality": 0.3
}
|
Prime_Transmit |
float |
0 |
1 |
0 |
Specifies the priming effect on transmission immunity for naive individuals (without natural or vaccine-derived immunity) for a multi-effect booster vaccine. |
{
"Prime_Transmit": 0.2
}
|
{
"Use_Defaults": 1,
"Campaign_Name": "Generic Seattle Regression Campaign",
"Events": [{
"Start_Day": 10,
"class": "CampaignEvent",
"Nodeset_Config": {
"class": "NodeSetAll"
},
"Event_Coordinator_Config": {
"class": "StandardInterventionDistributionEventCoordinator",
"Target_Demographic": "Everyone",
"Demographic_Coverage": 1.0,
"Intervention_Config": {
"class": "IndividualImmunityChanger",
"Cost_To_Consumer": 10.0,
"Prime_Acquire": 0.1,
"Prime_Transmit": 0.2,
"Prime_Mortality": 0.3,
"Boost_Acquire": 0.7,
"Boost_Transmit": 0.7,
"Boost_Mortality": 1.0,
"Boost_Threshold_Acquire": 0.2,
"Boost_Threshold_Transmit": 0.1,
"Boost_Threshold_Mortality": 0.1
}
}
}]
}